Descriptions:Total Iron Ion
Tags:Total Iron Ion
Descriptions:GAPDH
Tags:GAPDH
Descriptions:C-X-C motif chemokine 11 (CXCL11) also named Interferon-gamma-inducible protein 9 (IP-9), which is a chemokine of the intercrine alpha family. CXCL11 is a 8.8 kDa protein containing 79 amino acid residues. To CXCR3, CXCL11 has higher affinity than CXCL10 and CXCL9 which plays a role in immune activation. CXCL11 induces the activation of T cells which is also a chemotaxis for T cells. CXCL11 is produced in response for IFN Family.
Tags:CXCL11
Descriptions:C-X-C motif chemokine 13 (CXCL13) also named B lymphocyte chemoattractant (BLC), which is a chemokine of the intercrine alpha family. CXCL13 is a 7.9kDa protein containing 72 amino acid residues. CXCL13 is a chemotaxis for B lymphocyte. CXCL13 induces the cell proliferation though the AKT signal pathway which plays a key role intestinal cancer model. CXCL13 /CXCR5 axis is highly existed in gut, spleen and lymph nodes.
Applications:His tag
Tags:CXCL13
Descriptions:C-X-C motif chemokine 2 (CXCL2) also named Growth-regulated oncogene beta (GROβ), which is a chemokine of the intercrine alpha family. CXCL2 is a 8.1 kDa protein containing 73 amino acid residues. CXCL2 is often expressed in immune cells such as macrophages and monocytes. CXCL2 plays an important role with immune responses and cancer progression. CXCL2 activates the cell signal transduction with casepas1 that affects the cell proliferation, differentiation and migration.
Tags:CXCL2
Descriptions:Galectin-8 (Gal-8) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for β-galactoside binding, and the binding partners for galectin-8 have been identified, including CD44 and a subset of integrins. Galectin-8 and integrins form complexes, subsequently leading to phosphorylation of paxillin and focal adhesion kinase (FAK), which activates signal pathways including MAPK-ERK and PI3K-AKT pathways. Galectin-8 is constitutively presented in the Liver, kidney, cardiac muscle, lung, and brain. Galectin-8 serves as an immunosuppressive protective role against autoimmune CNS inflammation, regulating the balance of Th17 and Th1 polarization.
Tags:Galectin-8
Descriptions:Glial Cell Line-derived Neurotrophic Factor (GDNF) is the neurotrophic factor, belonging to the GDNF family of ligands (GFL) and identifying as a therapeutic candidate in Parkinson's disease.GDNF is a 23.7 kDa protein containing 211 residues that plays a critical role in promoting the survival and differentiation of midbrain dopamine neurons. Besides, GDNF is revealed to facilitate the development of peripheral tissues such as kidney, pancreas and lung. Additionally, as a member of GFL, GDNF also takes part in the progression of tumor.
Applications:His tag
Tags:GDNF
Descriptions:Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation.
Applications:His tag
Tags:BMP-12
Descriptions:PDHA
Tags:PDHA