Descriptions:转化生长因子-β3 (TGF-β3) 属于 TGF-β 超家族,TGF-β3 与 TGF-β1 和 TGF-β2 的相似度为 86% 和 91%。TGF-β3 是一个分子量为 12.8 kDa 的蛋白质,含有 412 个氨基酸,可以抑制 DNA 合成,促进细胞增殖,是心脏形态发生中 EMT 的重要介质,并且在乳汁淤积时上调,并诱导退化过程中乳腺上皮细胞凋亡。
Tags:TGF-β3
Descriptions:Human Sonic Hedgehog Protein, expressed in E. coli
Tags:SHH
Descriptions:脑源性营养神经因子 (BDNF) 是神经营养因子家族的成员,主要表达于海马、杏仁核、大脑皮层、下丘和小脑,也存在于和循环中。BDNF 是一个神经为 27.8 kDa 的蛋白质,含有 247 个残基,在调节中枢系统 (CNS) 各个区域的突触传递和可塑性方面发挥关键作用。还可以调节海马突触递中与记忆相关的长期增强效果。
Tags:BDNF
Descriptions:Human BAFF Protein, expressed in E. coli
Tags:BAFF
Descriptions:Sorbitol is widely found in animals, plants, microorganisms and cultured cells. It's a form of sugar transport, and also closely related to biological resistance and food flavor.
Tags:Sorbitol
Descriptions:Noggin是一种分子量为46.2 kDa的生物活性蛋白,以二硫键连接的同型二聚体形式存在(每条链23.1 kDa)。Noggin可与转化生长因子β(TGF-β)超家族信号蛋白成员结合,例如骨形态发生蛋白4(BMP-4),从而抑制其活性。作为BMP蛋白的细胞外拮抗剂,Noggin参与多种身体组织的发育,包括神经组织、肌肉和骨骼。此外,Noggin还能通过与GDF5相互作用来抑制软骨细胞分化。
Tags:Noggin
Descriptions:Bone Morphogenetic Protein-7 (BMP-7) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP7 can significantly inhibit TGF-β through binding with TGF-β receptor and trigger SMAD transcription factors, such as SMAD 1 /5/8. It plays a vital role in inhibiting the expansion of kidney damage and promoting the differentiation of osteoblasts.
Applications:His tag
Tags:BMP-7
Descriptions:Tyrosine ammonia lyase (TAL) is widely present in plants and microorganisms, and is one of the key enzymes in the phenylalanine metabolism pathway.
Descriptions:The Luminescent Mycoplasma Detection Kit utilizes Mycoplasma-specific kinase activity and detects it through a luminescent reaction catalyzed by ATP-dependent luciferase, and determines whether a sample is contaminated with Mycoplasma by comparing the change in ATP content before and after addition of the test reagent. When Mycoplasma is cleaved, it releases a unique kinase that reacts with the substrate and catalyzes the conversion of ADP to ATP.
Applications:Mycoplasma detection
Tags:Mycoplasma
Descriptions:Interleukin 19 (IL-19) predicts a molecular mass of 35.8 kDa, is a type of anti-inflammatory cytokine. It promotes the Th2 T-cell response which supports an anti-inflammatory lymphocyte phenotype, dampens the Th1 T-cell response and IFNγ secretion, increases IL-10 expression in peripheral blood mononuclear cells, and inhibits the production of IgG from B cells.
Tags:IL-19