| Product name | XRCC3 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human XRCC3 at AA range: 10-90 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | XRCC3; DNA repair protein XRCC3; X-ray repair cross-complementing protein 3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 38kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | XRCC3 encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. |
| Gene ID | 7517 |
| Alternative | XRCC3; DNA repair protein XRCC3; X-ray repair cross-complementing protein 3 |
| Others | XRCC3 Polyclonal Antibody detects endogenous levels of XRCC3 protein. |
| Accession | O43542 |
| Observed Band(KD) | 38 |
Fig. Western Blot analysis of various cells using XRCC3 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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