| Product name | XDH Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human XDH protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Xanthine dehydrogenase/oxidase; Xanthine oxidoreductase; XOR |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 146kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | XDH (Xanthine Dehydrogenase) is a Protein Coding gene. Diseases associated with XDH include Xanthinuria, Type I and Xanthinuria. Among its related pathways are Doxorubicin Pathway, Pharmacokinetics and Metabolism. XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. XDH can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in XDH cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. |
| Gene ID | 7498 |
| Alternative | Xanthine dehydrogenase/oxidase; Xanthine oxidoreductase; XOR |
| Others | The antibody detects endogenous levels of XDH protein |
| Accession | P47989 |
| Observed Band(KD) | 146 |
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