| Product name | WNK4 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human WNK4 protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Serine/threonine-protein kinase WNK4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 136kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | WNK4 (WNK Lysine Deficient Protein Kinase 4) encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in WNK4 result in pseudohypoaldosteronism type IIB. |
| Gene ID | 65266 |
| Alternative | Serine/threonine-protein kinase WNK4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4 |
| Others | The antibody detects endogenous levels of WNK4 protein |
| Accession | Q96J92 |
| Observed Band(KD) | 136 |
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