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VATG3 Polyclonal Antibody

VATG3 Polyclonal Antibody

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Specification

Product name VATG3 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human VATG3 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative V-type proton ATPase subunit G 3; V-ATPase subunit G 3; V-ATPase 13 kDa subunit 3; Vacuolar proton pump subunit G 3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 12kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background ATP6V1G3 (ATPase H+ Transporting V1 Subunit G3) is a Protein Coding gene. Among its related pathways are Rheumatoid arthritis and mTOR signaling pathway (KEGG). ATP6V1G3 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c" and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. ATP6V1G3 encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for ATP6V1G3.
Gene ID 127124
Alternative V-type proton ATPase subunit G 3; V-ATPase subunit G 3; V-ATPase 13 kDa subunit 3; Vacuolar proton pump subunit G 3
Others The antibody detects endogenous levels of VATG3 protein
Accession Q96LB4
Observed Band(KD) 12

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