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UIMC1 Polyclonal Antibody

UIMC1 Polyclonal Antibody

Views(5) Publications(0) Catalog no(ABP60852)
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Specification

Product name UIMC1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human UIMC1 protein
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative BRCA1-A complex subunit RAP80; Receptor-associated protein 80; Retinoid X receptor-interacting protein 110; Ubiquitin interaction motif-containing protein 1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 79kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background UIMC1 (Ubiquitin Interaction Motif Containing 1) is a Protein Coding gene. Among its related pathways are DNA Damage and DNA Double Strand Break Response. UIMC1 encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
Gene ID 51720
Alternative BRCA1-A complex subunit RAP80; Receptor-associated protein 80; Retinoid X receptor-interacting protein 110; Ubiquitin interaction motif-containing protein 1
Others The antibody detects endogenous levels of UIMC1 protein
Accession Q96RL1
Observed Band(KD) 79

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