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UB2D3 Polyclonal Antibody

UB2D3 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP60807)
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Specification

Product name UB2D3 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human UB2D3 protein
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Ubiquitin-conjugating enzyme E2 D3; E2 ubiquitin-conjugating enzyme D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 16kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background UBE2D3 (Ubiquitin Conjugating Enzyme E2 D3) is a Protein Coding gene. Diseases associated with UBE2D3 include Retinitis Pigmentosa 42. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Protein processing in endoplasmic reticulum. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
Gene ID 7323
Alternative Ubiquitin-conjugating enzyme E2 D3; E2 ubiquitin-conjugating enzyme D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3
Others The antibody detects endogenous levels of UB2D3 protein
Accession P61077
Observed Band(KD) 16

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