| Product name | Tuberin (phospho Ser939) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Tuberin around the phosphorylation site of S939 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 200kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Gene ID | 7249 |
| Alternative | TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein |
| Others | Phospho-Tuberin (S939) Polyclonal Antibody detects endogenous levels of Tuberin protein only when phosphorylated at S939. |
| Accession | P49815 |
| Observed Band(KD) | 200 |
Fig. Western Blot analysis of 293 cells using Phospho-Tuberin (S939) Polyclonal Antibody.
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