| Product name | TSHB Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human TSHB protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain; INN: Thyrotropin alfa |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 15kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by TSHB is the beta subunit of thyroid stimulating hormone. Mutations in TSHB are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of TSHB results in multiple transcript variants. |
| Gene ID | 7252 |
| Alternative | Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain; INN: Thyrotropin alfa |
| Others | The antibody detects endogenous levels of TSHB protein |
| Accession | P01222 |
| Observed Band(KD) | 15 |
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