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TRRAP Polyclonal Antibody

TRRAP Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP60774)
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Specification

Product name TRRAP Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human TRRAP protein
Host Rabbit
Reactivity Human,Mouse
Applications IHC,IF
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Transformation/transcription domain-associated protein; 350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homolog

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 424kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background TRRAP (Transformation/Transcription Domain Associated Protein) encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of TRRAP may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRRAP.
Gene ID 8295
Alternative Transformation/transcription domain-associated protein; 350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homolog
Others The antibody detects endogenous levels of TRRAP protein
Accession Q9Y4A5
Observed Band(KD) 424

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