| Product name | TNR21 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human TNR21 protein at amino acid sequence of 430-510 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Death receptor 6; CD_antigen: CD358 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 72kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | TNFRSF21 encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that TNFRSF21 plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. |
| Gene ID | 27242 |
| Alternative | Death receptor 6; CD_antigen: CD358 |
| Others | The antibody detects endogenous levels of TNR21 protein |
| Accession | O75509 |
| Observed Band(KD) | 72 |
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