| Product name | TIM-1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human TIM-1 protein at amino acid sequence of 40-100 |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell membrane protein 1; TIM-1; TIM |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 40-50kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by HAVCR1 is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of HAVCR1 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. HAVCR1 (Hepatitis A Virus Cellular Receptor 1) is a Protein Coding gene. Diseases associated with HAVCR1 include Hepatitis and Hepatitis A. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and NF-kappaB Signaling. |
| Gene ID | 26762 |
| Alternative | Hepatitis A virus cellular receptor 1; HAVcr-1; Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell membrane protein 1; TIM-1; TIM |
| Others | The antibody detects endogenous levels of TIM-1 |
| Accession | Q96D42 |
| Observed Band(KD) | 39 |
Fig.1. Western blot analysis of KB Hela 293T Mouse-brain lysate, antibody was diluted at 1:1000. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.
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