| Product name | Thrombospondin 4 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human Thrombospondin 4 protein at amino acid sequence of 551-600 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Thrombospondin-4 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by THBS4 belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. THBS4 is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. THBS4 (Thrombospondin 4) is a Protein Coding gene. Diseases associated with THBS4 include Mycetoma and Myocardial Infarction. Among its related pathways are Focal Adhesion and PI3K-Akt signaling pathway. |
| Gene ID | 7060 |
| Alternative | Thrombospondin-4 |
| Others | The antibody detects endogenous levels of Thrombospondin 4 |
| Accession | P35443 |
Fig.1. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200.
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