| Product name | THNS2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human THNS2 protein at amino acid sequence of 91-140 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 53kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | THNSL2 encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. |
| Gene ID | 55258 |
| Alternative | Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT |
| Others | The antibody detects endogenous levels of THNS2 protein |
| Accession | Q86YJ6 |
| Observed Band(KD) | 53 |
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