| Product name | TH (phospho Ser19) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human TH around the phosphorylation site of S19 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 45kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH. |
| Gene ID | 7054 |
| Alternative | TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH |
| Others | Phospho-TH (S19) Polyclonal Antibody detects endogenous levels of TH protein only when phosphorylated at S19. |
| Accession | P07101 |
| Observed Band(KD) | 45 |
Fig.1. Western Blot analysis of various cells using Phospho-TH (S19) Polyclonal Antibody diluted at 1:1000.
Fig.2. Western Blot analysis of 293 cells using Phospho-TH (S19) Polyclonal Antibody diluted at 1:1000.
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