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Tensin-2 (phospho Tyr483) Polyclonal Antibody

Tensin-2 (phospho Tyr483) Polyclonal Antibody

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Specification

Product name Tensin-2 (phospho Tyr483) Polyclonal Antibody
Immunogen Synthesized peptide derived from human Tensin-2 around the phosphorylation site of Y483
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 152kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The tensin 2 encoded by TNS belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Gene ID 23371
Alternative TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2
Others Phospho-Tensin-2 (Y483) Polyclonal Antibody detects endogenous levels of Tensin-2 protein only when phosphorylated at Y483.
Accession Q63HR2
Observed Band(KD) 152

Image & description

Fig.1. Western Blot analysis of 3T3 cells using Phospho-Tensin-2 (Y483) Polyclonal Antibody diluted at 1:2000.

Fig.1. Western Blot analysis of 3T3 cells using Phospho-Tensin-2 (Y483) Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of A549 NIH-3T3 SH-SY5Y K562 HELA cells using Phospho-Tensin-2 (Y483) Polyclonal Antibody diluted at 1:2000.

Fig.2. Western Blot analysis of A549 NIH-3T3 SH-SY5Y K562 HELA cells using Phospho-Tensin-2 (Y483) Polyclonal Antibody diluted at 1:2000.

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