| Product name | SYK (Phospho-Tyr348) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human SYK (Phospho-Tyr348) Antibody protein |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 82kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | SYK (Spleen Associated Tyrosine Kinase) is a Protein Coding gene. Diseases associated with SYK include Hantavirus Pulmonary Syndrome and Mycobacterium Abscessus. Among its related pathways are p70S6K Signaling and RET signaling. SYK encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Gene ID | 6850 |
| Alternative | Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk |
| Others | This antibody detects endogenous levels of SYK when Phospho occurs at Tyr348 |
| Accession | P43405 |
| Observed Band(KD) | 82 |
Fig.1. Western blot analysis of CACO2 lysate, antibody was diluted at 1:1000. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.
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