| Product name | SUMO4 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human SUMO4 protein |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Small ubiquitin-related modifier 4; SUMO-4; Small ubiquitin-like protein 4 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 10kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | SUMO4 is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. Small Ubiquitin-Like Modifier 4 described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. |
| Gene ID | 387082 |
| Alternative | Small ubiquitin-related modifier 4; SUMO-4; Small ubiquitin-like protein 4 |
| Others | The antibody detects endogenous levels of SUMO4 protein |
| Accession | Q6EEV6 |
| Observed Band(KD) | 10 |
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