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STK36 Polyclonal Antibody

STK36 Polyclonal Antibody

Views(2) Publications(0) Catalog no(ABP54544)
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Specification

Product name STK36 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human STK36 at AA rangle: 360-440
Host Rabbit
Reactivity Human,Mouse
Applications WB,IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 170kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background STK36 encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that STK36 is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.
Gene ID 27148
Alternative STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog
Others STK36 Polyclonal Antibody detects endogenous levels of STK36 protein.
Accession Q9NRP7
Observed Band(KD) 170

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