| Product name | Sodium Potassium ATPase alpha-1 (Phospho-Tyr260) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human Sodium Potassium ATPase alpha-1 (Phospho-Tyr260) Antibody protein at amino acid sequence of 230-290 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Sodium/potassium-transporting ATPase subunit alpha-1; Na(+/K(+ ATPase alpha-1 subunit; Sodium pump subunit alpha-1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 115kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. ATP1A1 encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for ATP1A1. |
| Gene ID | 476 |
| Alternative | Sodium/potassium-transporting ATPase subunit alpha-1; Na(+/K(+ ATPase alpha-1 subunit; Sodium pump subunit alpha-1 |
| Others | The antibody detects endogenous levels of Sodium Potassium ATPase alpha-1 when Phospho occurs at Tyr260 |
| Accession | P05023 |
| Observed Band(KD) | 115 |
Fig.1. Western blot analysis of KB Hela lysate, antibody was diluted at 1:1000. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.
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