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S10A7 Polyclonal Antibody

S10A7 Polyclonal Antibody

Views(5) Publications(0) Catalog no(ABP60289)
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Specification

Product name S10A7 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human S10A7 protein at amino acid sequence of 40-120
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Protein S100-A7; Psoriasin; S100 calcium-binding protein A7

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 11kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by S100A7 (S100 Calcium Binding Protein A7) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
Gene ID 6278
Alternative Protein S100-A7; Psoriasin; S100 calcium-binding protein A7
Others The antibody detects endogenous levels of S10A7 protein
Accession P31151
Observed Band(KD) 11

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