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RSPO2 Polyclonal Antibody

RSPO2 Polyclonal Antibody

Views(7) Publications(0) Catalog no(ABP60271)
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Specification

Product name RSPO2 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human RSPO2 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative R-spondin-2; Roof plate-specific spondin-2; hRspo2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 26kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background RSPO2 encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.
Gene ID 340419
Alternative R-spondin-2; Roof plate-specific spondin-2; hRspo2
Others The antibody detects endogenous levels of RSPO2 protein
Accession Q6UXX9
Observed Band(KD) 26

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