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RPB4 Polyclonal Antibody

RPB4 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP60242)
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Specification

Product name RPB4 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human RPB4 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative DNA-directed RNA polymerase II subunit RPB4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 15kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background POLR2D encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. POLR2D (RNA Polymerase II Subunit D) is a Protein Coding gene. Diseases associated with POLR2D include Myasthenic Syndrome, Congenital, 5. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and DNA damage_Role of Brca1 and Brca2 in DNA repair.
Gene ID 5433
Alternative DNA-directed RNA polymerase II subunit RPB4; DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit
Others The antibody detects endogenous levels of RPB4 protein
Accession O15514
Observed Band(KD) 15

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