| Product name | RN123 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human RN123 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | E3 ubiquitin-protein ligase RNF123; Kip1 ubiquitination-promoting complex protein 1; RING finger protein 123; RING-type E3 ubiquitin transferase RNF123 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 144kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The Ring Finger Protein 123 encoded by RNF123 contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants. RNF123 (Ring Finger Protein 123) is a Protein Coding gene. Among its related pathways are Deubiquitination and Class I MHC mediated antigen processing and presentation. |
| Gene ID | 63891 |
| Alternative | E3 ubiquitin-protein ligase RNF123; Kip1 ubiquitination-promoting complex protein 1; RING finger protein 123; RING-type E3 ubiquitin transferase RNF123 |
| Others | The antibody detects endogenous levels of RN123 protein |
| Accession | Q5XPI4 |
| Observed Band(KD) | 144 |
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