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RM19 Polyclonal Antibody

RM19 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP60199)
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Specification

Product name RM19 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human RM19 protein at amino acid sequence of 160-240
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative 39S ribosomal protein L19, mitochondrial; L19mt; MRP-L19; 39S ribosomal protein L15, mitochondrial; L15mt; MRP-L15; Mitochondrial large ribosomal subunit protein bL19m

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 32kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background MRPL19 (Mitochondrial Ribosomal Protein L19) is a Protein Coding gene. Diseases associated with MRPL19 include Reading Disorder. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL19 encodes a 39S subunit protein.
Gene ID 9801
Alternative 39S ribosomal protein L19, mitochondrial; L19mt; MRP-L19; 39S ribosomal protein L15, mitochondrial; L15mt; MRP-L15; Mitochondrial large ribosomal subunit protein bL19m
Others The antibody detects endogenous levels of RM19 protein
Accession P49406
Observed Band(KD) 32

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