| Product name | Rat IL-6 Protein |
| Sequence | Amino acid sequence derived from Rat IL-6 P20607 (F25-T211) was expressed. |
| Activity | Testing in Progress |
| Protein length | The Rat Rat IL-6 consists of 187 amino acids and predicts a molecular mass of 21.73KDa. |
| Preparation method | E. coli |
| Purity | > 99 % as determined by SDS-PAGE |
| Alternative | Interleukin6;IL-6;IL6;IL 6;MGI2-A;MGI2A;HGF;BSF2;HSF;IFNB2;B-Cell Stimulatory Factor-2;Hybridoma/Plasmacytoma Growth Factor;Hepatocyte Stimulating Factor;Cytotoxic T-Cell Differentiation Factor |
| Formulation | Lyophilized from sterile 20mM Tris，0.15M NaCl, pH 7.4. |
| Molecular weight | 21.73 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-3 protein using the buffer we provided (10 mM HCl) not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized Human IL-3 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Shipping | The product is shipped at ambient temperature. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity. |
| Gene ID | M26744.1 |
| Alternative | Interleukin6;IL-6;IL6;IL 6;MGI2-A;MGI2A;HGF;BSF2;HSF;IFNB2;B-Cell Stimulatory Factor-2;Hybridoma/Plasmacytoma Growth Factor;Hepatocyte Stimulating Factor;Cytotoxic T-Cell Differentiation Factor |
| Accession | P20607 |
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1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
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