| Product name | Rat IL-1β protein |
| Sequence | Amino acid sequence derived from Rat IL-1β protein (Q63264) (Val117-Ser268) was expressed. |
| Activity | Immobilized Rat IL-1β at 1 μg/mL (100 μl/well) can bind Mouse IL-1R1 with a linear range of 22.86 ug/mL. |
| Protein length | The recombinant Rat IL-1β protein consists of 152 amino acids and has a predicted molecular mass of 17.4 kDa. |
| Preparation method | E. coli |
| Purity | >98% as determined by SDS-PAGE |
| Alternative | IL-1; IL-1β; IL-1 beta; IL-1B; IL1-BETA; IL1F2; Interleukin-1 beta; IL1B |
| Formulation | Lyophilized from sterile 20 mM Tris with 150 mM NaCl, pH 7.4. |
| Features & Benefits | Endotoxin:< 1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 17.4 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Rat IL-1β protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized Rat IL-1β protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Interleukin-1β (IL-1β) also known as catabolin, is a member of the interleukin 1 cytokine family. IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. IL-1β is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by Interleukin 1β in the central nervous system (CNS). IL-1β gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| Gene ID | 24494 |
| Alternative | IL-1; IL-1β; IL-1 beta; IL-1B; IL1-BETA; IL1F2; Interleukin-1 beta; IL1B |
Fig.SDS-PAGE analysis of Rat IL-1β protein
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