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RASM Polyclonal Antibody

RASM Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP60101)
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Specification

Product name RASM Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human RASM protein
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Ras-related protein M-Ras; Ras-related protein R-Ras3

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 22kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background MRAS encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. MRAS (Muscle RAS Oncogene Homolog) is a Protein Coding gene. Diseases associated with MRAS include Vertebral Artery Occlusion and Causalgia. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and p70S6K Signaling.
Gene ID 22808
Alternative Ras-related protein M-Ras; Ras-related protein R-Ras3
Others The antibody detects endogenous levels of RASM protein
Accession O14807
Observed Band(KD) 22

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