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PURB Polyclonal Antibody

PURB Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP60047)
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Specification

Product name PURB Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human PURB protein
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Transcriptional activator protein Pur-beta; Purine-rich element-binding protein B

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 34kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PURB (Purine Rich Element Binding Protein B) product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of PURB has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
Gene ID 5814
Alternative Transcriptional activator protein Pur-beta; Purine-rich element-binding protein B
Others The antibody detects endogenous levels of PURB protein
Accession Q96QR8
Observed Band(KD) 34

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