| Product name | PTPRT Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human PTPRT protein at amino acid sequence of 200-280 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Receptor-type tyrosine-protein phosphatase T; R-PTP-T; Receptor-type tyrosine-protein phosphatase rho; RPTP-rho |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 158kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by PTPRT is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRT possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of PTPRT suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of PTPRT, which encode distinct proteins, have been reported. |
| Gene ID | 11122 |
| Alternative | Receptor-type tyrosine-protein phosphatase T; R-PTP-T; Receptor-type tyrosine-protein phosphatase rho; RPTP-rho |
| Others | The antibody detects endogenous levels of PTPRT protein |
| Accession | O14522 |
| Observed Band(KD) | 158 |
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