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PRLR Polyclonal Antibody

PRLR Polyclonal Antibody

Views(5) Publications(0) Catalog no(ABP60001)
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Specification

Product name PRLR Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human PRLR protein at amino acid sequence of 80-160
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Prolactin receptor; PRL-R

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 68kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for PRLR, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Gene ID 5618
Alternative Prolactin receptor; PRL-R
Others The antibody detects endogenous levels of PRLR protein
Accession P16471
Observed Band(KD) 68

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