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PPR3D Polyclonal Antibody

PPR3D Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59989)
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Specification

Product name PPR3D Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human PPR3D protein at amino acid sequence of 10-90
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Protein phosphatase 1 regulatory subunit 3D; Protein phosphatase 1 regulatory subunit 6; PP1 subunit R6; Protein phosphatase 1-binding subunit R6

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 32kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. PPP1R3D (Protein Phosphatase 1 Regulatory Subunit 3D) encodes a glycogen-targeting subunit of PP1.
Gene ID 5509
Alternative Protein phosphatase 1 regulatory subunit 3D; Protein phosphatase 1 regulatory subunit 6; PP1 subunit R6; Protein phosphatase 1-binding subunit R6
Others The antibody detects endogenous levels of PPR3D protein
Accession O95685
Observed Band(KD) 32

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