| Product name | PNPase Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human PNPase at AA range: 540-620 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | PNPT1; PNPASE; Polyribonucleotide nucleotidyltransferase 1; mitochondrial; 3'-5' RNA exonuclease OLD35; PNPase old-35; Polynucleotide phosphorylase 1; PNPase 1; Polynucleotide phosphorylase-like protein |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 85kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Polyribonucleotide nucleotidyltransferase 1 encoded by PNPT1 elongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. Polyribonucleotide nucleotidyltransferase 1 is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. |
| Gene ID | 87178 |
| Alternative | PNPT1; PNPASE; Polyribonucleotide nucleotidyltransferase 1; mitochondrial; 3'-5' RNA exonuclease OLD35; PNPase old-35; Polynucleotide phosphorylase 1; PNPase 1; Polynucleotide phosphorylase-like protein |
| Others | PNPase Polyclonal Antibody detects endogenous levels of PNPase protein. |
| Accession | Q8TCS8 |
| Observed Band(KD) | 85 |
Fig. Western Blot analysis of various cells using PNPase Polyclonal Antibody diluted at 1:1000.
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