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PMCH Polyclonal Antibody

PMCH Polyclonal Antibody

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Specification

Product name PMCH Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human PMCH protein at amino acid sequence of 112-161
Host Rabbit
Reactivity Human,Mouse,Rat
Applications IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Pro-MCH

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PMCH encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include melanin-concentrating hormone (MCH), neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). Melanin-concentrating hormone is a 19-amino acid neuropeptide that stimulates hunger and may additionally regulate energy homeostasis, reproductive function, and sleep. Pseudogenes of PMCH have been identified on chromosome 5. PMCH (Pro-Melanin Concentrating Hormone) is a Protein Coding gene. Diseases associated with PMCH include Hypersomnia and Byssinosis. Among its related pathways are Signaling by GPCR and RET signaling.
Gene ID 5367
Alternative Pro-MCH
Others The antibody detects endogenous levels of PMCH
Accession P20382

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.

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