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PLEC Polyclonal Antibody

PLEC Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP59939)
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Specification

Product name PLEC Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human PLEC protein at amino acid sequence of 240-320
Host Rabbit
Reactivity Human,Rat,Mouse
Applications IHC,IF
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 515kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PLEC (Plectin) is a Protein Coding gene. Diseases associated with PLEC include Epidermolysis Bullosa Simplex, Ogna Type and Muscular Dystrophy, Limb-Girdle, Type 2Q. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Collagen chain trimerization. PLEC is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton.
Gene ID 5339
Alternative Plectin; PCN; PLTN; Hemidesmosomal protein 1; HD1; Plectin-1
Others The antibody detects endogenous levels of PLEC protein
Accession Q15149
Observed Band(KD) 515

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