| Product name | pICln Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human pICln at AA range: 160-240 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I(Cln); Chloride ion current inducer protein; ClCI; Reticulocyte pICln |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 37kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | T CLNS1A encodes a protein that functions in multiple regulatory pathways. Chloride nucleotide-sensitive channel 1A complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. Chloride nucleotide-sensitive channel 1A is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of CLNS1A are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for CLNS1A. |
| Gene ID | 1207 |
| Alternative | CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I(Cln); Chloride ion current inducer protein; ClCI; Reticulocyte pICln |
| Others | pICln Polyclonal Antibody detects endogenous levels of pICln protein. |
| Accession | P54105 |
| Observed Band(KD) | 37 |
Fig. Western Blot analysis of various cells using pICln Polyclonal Antibody.
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