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PI 3-Kinase p85β Polyclonal Antibody

PI 3-Kinase p85β Polyclonal Antibody

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Specification

Product name PI 3-Kinase p85β Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human PI 3-Kinase p85β protein at amino acid sequence of 1-60
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Phosphatidylinositol 3-kinase regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-beta

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by PIK3R2 is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for PIK3R2. PIK3R2 (Phosphoinositide-3-Kinase Regulatory Subunit 2) is a Protein Coding gene. Diseases associated with PIK3R2 include Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 and Mpph Syndrome. Among its related pathways are 4-1BB Pathway and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.
Gene ID 5296
Alternative Phosphatidylinositol 3-kinase regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; PI3-kinase subunit p85-beta; PtdIns-3-kinase regulatory subunit p85-beta
Others The antibody detects endogenous levels of PI 3-Kinase p85β
Accession O00459

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded Human-testis, antibody was diluted at 1:100.

Fig.1. Immunohistochemical analysis of paraffin-embedded Human-testis, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human-testis, antibody was diluted at 1:100.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human-testis, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded Human-colon, antibody was diluted at 1:100.

Fig.3. Immunohistochemical analysis of paraffin-embedded Human-colon, antibody was diluted at 1:100.

Fig.4. Immunohistochemical analysis of paraffin-embedded Human-colon, antibody was diluted at 1:100.

Fig.4. Immunohistochemical analysis of paraffin-embedded Human-colon, antibody was diluted at 1:100.

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