| Product name | PHB2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human PHB2 protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 32kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | PHB2 (Prohibitin 2) is a Protein Coding gene. Diseases associated with PHB2 include Urethritis and Loiasis. Among its related pathways are GPCR Pathway and MAPK Signaling: mitogen Stimulation Pathway. GO annotations related to this gene include estrogen receptor binding. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. |
| Gene ID | 11331 |
| Alternative | B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity |
| Others | The antibody detects endogenous levels of PHB2 protein |
| Accession | Q99623 |
| Observed Band(KD) | 32 |
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