| Product name | PDE7A Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human PDE7A protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; HCP1; TM22 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 53kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE7A. PDE7A (Phosphodiesterase 7A) is a Protein Coding gene. Diseases associated with PDE7A include Chronic Lymphocytic Leukemia and Low Compliance Bladder. Among its related pathways are G alpha(s) signalling events and Ectoderm Differentiation. |
| Gene ID | 5150 |
| Alternative | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; HCP1; TM22 |
| Others | The antibody detects endogenous levels of PDE7A protein |
| Accession | Q13946 |
| Observed Band(KD) | 53 |
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