| Product name | Paxillin (phospho Tyr88) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Paxillin around the phosphorylation site of Y88 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | PXN; Paxillin |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 68kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | PXN encodes a cytoskeletal protein (paxillin) involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN.These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). |
| Gene ID | 5829 |
| Alternative | PXN; Paxillin |
| Others | Phospho-Paxillin (Y88) Polyclonal Antibody detects endogenous levels of Paxillin protein only when phosphorylated at Y88. |
| Accession | P49023 |
| Observed Band(KD) | 68 |
Fig. Western Blot analysis of various cells using Phospho-Paxillin (Y88) Polyclonal Antibody.
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