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P2RY1 Polyclonal Antibody

P2RY1 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP59788)
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Specification

Product name P2RY1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human P2RY1 protein at amino acid sequence of 130-210
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative P2Y purinoceptor 1; P2Y1; ATP receptor; Purinergic receptor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 41kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The product of P2RY1 gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Gene ID 5028
Alternative P2Y purinoceptor 1; P2Y1; ATP receptor; Purinergic receptor
Others The antibody detects endogenous levels of P2RY1 protein
Accession P47900
Observed Band(KD) 41

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