| Product name | NRG4 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human NRG4 protein at amino acid sequence of 11-60 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Pro-neuregulin-4, membrane-bound isoform; Pro-NRG4 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 12kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | NRG4 (Neuregulin 4) is a Protein Coding gene. Among its related pathways are RET signaling and Signaling by ERBB2. GO annotations related to this gene include receptor binding and growth factor activity. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity). |
| Gene ID | 145957 |
| Alternative | Pro-neuregulin-4, membrane-bound isoform; Pro-NRG4 |
| Others | The antibody detects endogenous levels of NRG4 protein |
| Accession | Q8WWG1 |
| Observed Band(KD) | 12 |
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