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NR0B2 Polyclonal Antibody

NR0B2 Polyclonal Antibody

Views(6) Publications(0) Catalog no(ABP59520)
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Specification

Product name NR0B2 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NR0B2 protein at amino acid sequence of 30-110
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Nuclear receptor subfamily 0 group B member 2; Orphan nuclear receptor SHP; Small heterodimer partner

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 28kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by NR0B2 (Nuclear Receptor Subfamily 0 Group B Member 2) is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. NR0B2 product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation.
Gene ID 8431
Alternative Nuclear receptor subfamily 0 group B member 2; Orphan nuclear receptor SHP; Small heterodimer partner
Others The antibody detects endogenous levels of NR0B2 protein
Accession Q15466
Observed Band(KD) 28

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