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NPHP1 Polyclonal Antibody

NPHP1 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59506)
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Specification

Product name NPHP1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NPHP1 protein at amino acid sequence of 510-590
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Nephrocystin-1; Juvenile nephronophthisis 1 protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 80kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NPHP1 (Nephrocystin 1) is a Protein Coding gene. Diseases associated with NPHP1 include Senior-Loken Syndrome-1 and Nephronophthisis 1, Juvenile. Among its related pathways are Organelle biogenesis and maintenance and Regulation of PLK1 Activity at G2/M Transition. NPHP1 encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures.
Gene ID 4867
Alternative Nephrocystin-1; Juvenile nephronophthisis 1 protein
Others The antibody detects endogenous levels of NPHP1 protein
Accession O15259
Observed Band(KD) 80

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