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NKAP Polyclonal Antibody

NKAP Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP59470)
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Specification

Product name NKAP Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NKAP protein at amino acid sequence of 10-90
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative NF-kappa-B-activating protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 45kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NKAP encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Gene ID 79576
Alternative NF-kappa-B-activating protein
Others The antibody detects endogenous levels of NKAP protein
Accession Q8N5F7
Observed Band(KD) 45

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