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NCK1 Polyclonal Antibody

NCK1 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59409)
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Specification

Product name NCK1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NCK1 protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Cytoplasmic protein NCK1; NCK adaptor protein 1; Nck-1; SH2/SH3 adaptor protein NCK-alpha

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 41kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NCK1 (NCK Adaptor Protein 1) is a Protein Coding gene. Diseases associated with NCK1 include Wiskott-Aldrich Syndrome and Multiple Endocrine Neoplasia Iib. Among its related pathways are Netrin-1 signaling and Arf6 signaling events. The protein encoded by NCK1 is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Gene ID 4690
Alternative Cytoplasmic protein NCK1; NCK adaptor protein 1; Nck-1; SH2/SH3 adaptor protein NCK-alpha
Others The antibody detects endogenous levels of NCK1 protein
Accession P16333
Observed Band(KD) 41

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