| Product name | Napsin A Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human Napsin A protein at amino acid sequence of 191-240 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Napsin-A; Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | NAPSA encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. NAPSA has been described as a marker for lung adenocarcinoma and renal cell carcinoma. |
| Gene ID | 9476 |
| Alternative | Napsin-A; Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02 |
| Others | The antibody detects endogenous levels of Napsin A |
| Accession | O96009 |
Fig.1. Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.
Fig.4. Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.
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