| Product name | N2DL2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human N2DL2 protein |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | UL16-binding protein 2; ALCAN-alpha; NKG2D ligand 2; N2DL-2; NKG2DL2; Retinoic acid early transcript 1H |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 27kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. ULBP2 is located in a cluster of multiple MHC class I-related genes on chromosome 6. ULBP2 (UL16 Binding Protein 2) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and p53 Pathway (RnD). |
| Gene ID | 80328 |
| Alternative | UL16-binding protein 2; ALCAN-alpha; NKG2D ligand 2; N2DL-2; NKG2DL2; Retinoic acid early transcript 1H |
| Others | The antibody detects endogenous levels of N2DL2 protein |
| Accession | Q9BZM5 |
| Observed Band(KD) | 27 |
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