| Product name | MYOZ2 Polyclonal Antibody |
| Immunogen | Synthetic peptide from human protein at AA range: 21-70 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA,IHC |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | MYOZ2; C4orf5 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 30kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by MYOZ2 (myozenin 2) belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in MYOZ2 cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. |
| Gene ID | 51778 |
| Alternative | MYOZ2; C4orf5 |
| Others | The antibody detects endogenous MYOZ2 protein. |
| Accession | Q9NPC6 |
| Observed Band(KD) | 30 |
Fig. Western Blot analysis of hepg2 cells using Antibody diluted at 1:500. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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